Description

(2S)-2-(3-Oxo-1,2-Benzisothiazol-2(3H)-Yl)-Propanoic Acid is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with specific stereochemistry, which is critical for biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and development of new therapeutic agents, particularly where the (S)-enantiomer configuration is required for efficacy.
• Organic Synthesis Research: Used as a specialized building block in academic and industrial laboratories for constructing benzisothiazolone-based compounds and studying structure-activity relationships.
• Agrochemical Development: Potential application as an intermediate in the synthesis of novel, enantiomerically pure crop protection agents and herbicides.
• Material Science Precursor: Can be utilized in the development of advanced functional materials, such as chiral ligands for catalysis or monomers for specialty polymers.

Basic Information

Product Name	(2S)-2-(3-Oxo-1,2-Benzisothiazol-2(3H)-Yl)-Propanoic Acid
CAS No.	1212358-67-2
Molecular Formula	C10H9NO3S
Molecular Weight	223.25 g/mol
Synonyms	(S)-2-(3-Oxo-1,2-benzisothiazol-2(3H)-yl)propanoic acid; (2S)-2-(3-Oxobenzo[d]isothiazol-2(3H)-yl)propanoic acid; (S)-2-(3-Oxobenzo[d]isothiazol-2(3H)-yl)propanoic acid; (S)-2-(1,1-Dioxido-1,2-benzisothiazol-3(2H)-yl)propanoic acid (tautomer); L-2-(3-Oxo-1,2-benzisothiazol-2(3H)-yl)propionic acid; Saccharin derivative (S)-isomer; (S)-2-(3-Oxo-2,3-dihydrobenzo[d]isothiazol-2-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our (2S)-2-(3-Oxo-1,2-Benzisothiazol-2(3H)-Yl)-Propanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.