Description

cis-2-Hydroxymethyl-1-Methyl-1-Cyclohexylamine Hydrochloride is a high-purity, functionalized cyclohexylamine derivative offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a versatile chiral building block and intermediate in advanced organic synthesis, where its defined stereochemistry and amine functionality are critical. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring complex cyclohexane-based structures.
• Academic & Contract Research: Essential material for methodological studies in organic chemistry and process development within academic and CRO (Contract Research Organization) laboratories.
• Material Science: Potential monomer or additive for advanced polymeric materials, where its functional groups can modify material properties.

Basic Information

Product Name	cis-2-Hydroxymethyl-1-Methyl-1-Cyclohexylamine Hydrochloride
CAS No.	1212253-95-6
Molecular Formula	C9H19NO • HCl
Molecular Weight	193.72 g/mol (Free base: 157.25 g/mol)
Synonyms	(1R,2S)-2-(Hydroxymethyl)-1-methylcyclohexanamine Hydrochloride; (1S,2R)-2-(Hydroxymethyl)-1-methylcyclohexanamine Hydrochloride; cis-1-Amino-2-(hydroxymethyl)-1-methylcyclohexane Hydrochloride; 1-Methyl-2-(hydroxymethyl)cyclohexylamine Hydrochloride (cis-); trans-2-Hydroxymethyl-1-methyl-1-cyclohexylamine Hydrochloride (Isomer); Aminomethylmethylcyclohexanol Hydrochloride; Cyclohexanamine derivative hydrochloride
EINECS	Contact for details

Quality Control

Our cis-2-Hydroxymethyl-1-Methyl-1-Cyclohexylamine Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and consistent stereochemical integrity. We provide full traceability and detailed Certificates of Analysis (COA) upon request, which include data from chiral HPLC, NMR, and mass spectrometry. Our quality commitment supports cGMP and ISO-guided practices for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.