Description

trans-6-Aminomethyl-Cyclohex-3-Enylamine Dihydrochloride is a high-purity, functionalized cyclohexene derivative with a diamine structure, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, bicyclic scaffold with two distinct amine handles, enabling the construction of complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for central nervous system (CNS) targets and bioactive natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as for hydrogenation or C-C bond-forming reactions.
• Peptidomimetics: Incorporated into peptide backbones to create conformationally restricted analogs with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and receptor interactions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers with amine-reactive sites.

Basic Information

Item	Details
Product Name	trans-6-Aminomethyl-Cyclohex-3-Enylamine Dihydrochloride
CAS No.	1212137-93-3
Molecular Formula	C8H18Cl2N2
Molecular Weight	213.15 g/mol
Synonyms	trans-6-(Aminomethyl)cyclohex-3-ene-1-amine dihydrochloride; (1R,6S)-6-(Aminomethyl)cyclohex-3-en-1-amine dihydrochloride; (1S,6R)-6-(Aminomethyl)cyclohex-3-en-1-amine dihydrochloride; 3-Cyclohexene-1-methanamine, 6-amino-, hydrochloride (1:2), trans-; 6-Aminomethyl-3-cyclohexene-1-amine dihydrochloride; trans-1,6-Diaminomethyl-3-cyclohexene dihydrochloride; (trans)-6-(Aminomethyl)cyclohex-3-en-1-amine dihydrochloride
EINECS	Contact for details

Quality Control

Our trans-6-Aminomethyl-Cyclohex-3-Enylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.