Description

Dichloro[1,3-Bis(2,6-Diisopropylphenyl)Imidazolidin-2-Ylidene][(5-(2-Ethoxy-2-Oxoethanamido))-(2-Isopropoxy)Benzylidene]Ruthenium(II) is a highly specialized, second-generation Grubbs-Hoveyda type olefin metathesis catalyst, distinguished by its modified N-heterocyclic carbene (NHC) ligand and functionalized benzylidene ether. This compound matters for its exceptional thermal stability and functional group tolerance, enabling challenging cross-metathesis and ring-closing metathesis reactions under mild conditions. It is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for the efficient synthesis of complex molecules and polymers.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key ring-closing metathesis (RCM) steps in the production of active pharmaceutical ingredients (APIs) and complex macrocyclic compounds.
• Agrochemical Research: Facilitating the construction of novel, bioactive ring systems for new crop protection agents and herbicides.
• Advanced Polymer Chemistry: Serving as a precision catalyst for ring-opening metathesis polymerization (ROMP) to create specialized polymers with tailored properties for electronics and coatings.
• Fine Chemical Production: Catalyzing efficient cross-metathesis (CM) reactions for the synthesis of high-value olefins and specialty chemicals.
• Academic & Industrial R&D: A vital tool for methodology development in organic synthesis and catalysis research within university and corporate laboratories.
• Material Science: Used in the development of self-healing materials and novel organic-inorganic hybrid frameworks via surface-initiated metathesis.

Basic Information

Item	Details
Product Name	Dichloro[1,3-Bis(2,6-Diisopropylphenyl)Imidazolidin-2-Ylidene][(5-(2-Ethoxy-2-Oxoethanamido))-(2-Isopropoxy)Benzylidene]Ruthenium(II)
CAS No.	1212009-08-9
Molecular Formula	C46H62Cl2N2O4Ru
Molecular Weight	884.97 g/mol
Synonyms	Modified Hoveyda-Grubbs Catalyst 2nd Generation; Functionalized Hoveyda-Grubbs Catalyst; Ruthenium-based Olefin Metathesis Catalyst; [1,3-Bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene]dichloro[[5-[(2-ethoxy-2-oxoethyl)amino]-2-isopropoxyphenyl]methylene]ruthenium; NHC-Ru Catalyst; Grubbs-Hoveyda Type Complex; (2-Isopropoxy-5-(2-ethoxy-2-oxoacetamido)benzylidene) Ruthenium Complex
EINECS	Contact for details

Quality Control

Every batch of our ruthenium metathesis catalysts is produced and handled under a strict quality management system. The product undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to confirm identity, purity, and catalytic activity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific results. Our commitment ensures the reproducibility and reliability required for sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade catalytic performance. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark green to brown crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Elemental Analysis (C, H, N)	Within ± 0.4% of theoretical
Residual Solvents (GC)	Complies with ICH guidelines
Catalytic Activity Test	Pass (Standard RCM reaction)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.