Description

3-Chloro-4-{[6-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Aniline is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in agrochemical and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector working on innovative crop protection agents and targeted therapeutics. The specific structure offers unique reactivity for constructing complex molecules.

Application

• Agrochemical Intermediate: A key precursor in the research and synthesis of next-generation herbicides and insecticides, leveraging the trifluoromethylpyridyloxy aniline scaffold for enhanced bioactivity.
• Pharmaceutical Intermediate: Serves as a crucial building block for developing novel small-molecule drug candidates, particularly in areas requiring halogenated aniline derivatives.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new chemical entities and reaction pathways in heterocyclic and fluorine chemistry.
• Material Science Precursor: Potential use in the synthesis of specialized ligands, dyes, or functional materials due to its electron-rich aniline and electron-deficient pyridine components.

Basic Information

Product Name	3-Chloro-4-{[6-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Aniline
CAS No.	1211669-81-6
Molecular Formula	C12H8ClF3N2O
Molecular Weight	288.65 g/mol
Synonyms	3-Chloro-4-((6-(trifluoromethyl)pyridin-2-yl)oxy)aniline; 2-[(3-Chloro-4-aminophenoxy]-6-(trifluoromethyl)pyridine; 3-Chloro-4-[(6-trifluoromethyl-2-pyridyl)oxy]aniline; 3-Chloro-4-(6-(trifluoromethyl)pyridin-2-yloxy)benzenamine; 1211669-81-6; 3-Chloro-4-{[6-(trifluoromethyl)-2-pyridinyl]oxy}aniline; 3-Chloro-4-((6-(trifluoromethyl)-2-pyridinyl)oxy)benzenamine
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-{[6-(Trifluoromethyl)Pyridin-2-Yl]Oxy}Aniline adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.