Description

Spiro[1H-Indene-1,2'-Pyrrolidine], 6-Bromo-2,3-Dihydro- is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in developing new therapeutic agents, especially within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in the development of new synthetic methodologies and the construction of complex spirocyclic and heterocyclic compounds.
• Drug Discovery Programs: Particularly relevant in the research of potential therapies targeting neurological disorders and various cancers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical development pipelines.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and pharmacology.

Basic Information

Product Name	Spiro[1H-Indene-1,2'-Pyrrolidine], 6-Bromo-2,3-Dihydro-
CAS No.	1211594-29-4
Molecular Formula	C12H12BrN
Molecular Weight	250.14 g/mol
Synonyms	6-Bromo-2,3-dihydrospiro[indene-1,2'-pyrrolidine]; 6-Bromo-2,3-dihydro-1'H-spiro[indene-1,2'-pyrrolidine]; 6-Bromospiro[indene-1,2'-pyrrolidine]; 6-Bromo-2,3-dihydrospiro[indene-1,2'-pyrrolidine]; 1211594-29-4; Spiro[indene-1,2'-pyrrolidine], 6-bromo-2,3-dihydro-; 6-Bromo-2,3-dihydro-1H-spiro[indene-1,2'-pyrrolidine]
EINECS	Contact for details

Quality Control

Our Spiro[1H-Indene-1,2'-Pyrrolidine], 6-Bromo-2,3-Dihydro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.