Description

5-Fluoro-2,3-Dihydrospiro[Indene-1,2'-Pyrrolidine] is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug molecules, especially those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• CNS Drug Development: Serves as a core scaffold for developing compounds aimed at neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes to study biological pathways and protein functions.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific projects.

Basic Information

Product Name	5-Fluoro-2,3-Dihydrospiro[Indene-1,2'-Pyrrolidine]
CAS No.	1211594-23-8
Molecular Formula	C12H14FN
Molecular Weight	191.25 g/mol
Synonyms	5-Fluoro-2,3-dihydrospiro[indene-1,2'-pyrrolidine]; 5-Fluoro-2,3-dihydro-1H-spiro[indene-1,2'-pyrrolidine]; 5-Fluoro-1H-spiro[indene-1,2'-pyrrolidine]; 5-Fluoro-2,3-dihydrospiro[indene-1,2'-pyrrolidine]; 5-Fluoro-2,3-dihydrospiro[indene-1,2'-pyrrolidine] (CAS 1211594-23-8); 5-Fluoro-2,3-dihydrospiro[indene-1,2'-pyrrolidine] hydrochloride (if applicable); Spiro[indene-1,2'-pyrrolidine], 5-fluoro-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2,3-Dihydrospiro[Indene-1,2'-Pyrrolidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.