Description

8-Chloro-1-Iodoimidazo[1,5-A]Pyrazine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical candidates and agrochemicals, enabling critical structural modifications. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development and discovery of new active ingredients for crop protection products, leveraging its unique halogenated structure.
• Chemical Biology Probe Synthesis: Employed to create specialized molecular probes for studying biological pathways and target engagement.
• Material Science Research: Acts as a building block for creating novel organic electronic materials or ligands for catalytic systems.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it a valuable substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis for High-Throughput Screening: Utilized in combinatorial chemistry to generate diverse compound libraries for biological activity screening.

Basic Information

Product Name	8-Chloro-1-Iodoimidazo[1,5-A]Pyrazine
CAS No.	1211591-21-7
Molecular Formula	C6H3ClIN3
Molecular Weight	279.47 g/mol
Synonyms	8-Chloro-1-iodoimidazo[1,5-a]pyrazine; Imidazo[1,5-a]pyrazine, 8-chloro-1-iodo-; 1-Iodo-8-chloroimidazo[1,5-a]pyrazine; 8-Chloro-1-iodo-imidazo[1,5-a]pyrazine; CAS 1211591-21-7
EINECS	Contact for details

Quality Control

Our 8-Chloro-1-Iodoimidazo[1,5-A]Pyrazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.