Description

3-Bromo-2-(trifluoromethyl)isonicotinic acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl substituents on the pyridine ring, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts, enabling novel synthetic transformations.
• Material Science Research: Acts as a building block for creating functional organic materials, such as liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D projects.

Basic Information

Product Name	3-Bromo-2-(trifluoromethyl)isonicotinic Acid
CAS No.	1211588-27-0
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	3-Bromo-2-(trifluoromethyl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-bromo-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-3-bromoisonicotinic acid; 3-Bromo-2-trifluoromethylisonicotinic acid; 3-Bromo-2-(trifluoromethyl)-4-pyridinecarboxylic acid; Isonicotinic acid, 3-bromo-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(trifluoromethyl)isonicotinic acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.