Description

2-Methyl-5-(Trifluoromethyl)Nicotinic Acid is a high-value, multi-functional chemical intermediate characterized by its nicotinic acid core and trifluoromethyl substituent. This compound is essential for the synthesis of advanced molecules, where its structure imparts desirable properties such as metabolic stability and enhanced lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Research: Investigated as a monomer or additive for developing advanced polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways in academic and industrial research.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Nicotinic Acid
CAS No.	1211581-65-5
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	5-(Trifluoromethyl)-2-methylpyridine-3-carboxylic acid; 2-Methyl-5-trifluoromethylnicotinic acid; 3-Pyridinecarboxylic acid, 2-methyl-5-(trifluoromethyl)-; 2-Methyl-5-(trifluoromethyl)-3-pyridinecarboxylic acid; 2-Methyl-5-(trifluoromethyl)nicotinate (acid); 1211581-65-5; 2-Methyl-5-(trifluoromethyl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Nicotinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.