Description

5-Bromo-3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and diagnostic agents in life science research.

Basic Information

Product Name	5-Bromo-3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	1211580-84-5
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-bromo-3-(trifluoromethyl)-; 5-Bromo-3-trifluoromethylpicolinic acid; 5-Bromo-3-(trifluoromethyl)picolinic acid; 5-Bromo-3-(trifluoromethyl)-2-pyridinecarboxylic acid; 1211580-84-5; 5-Br-3-CF3-Py-2-COOH
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for our fine chemical intermediates. Each batch of 5-Bromo-3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is analyzed using advanced techniques like HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support audits to ensure compliance with your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.