Description

2-Bromo-5-Methyl-4-Pyridinecarboxylic Acid is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity, enabling the introduction of both bromine and carboxylic acid functional groups into complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	2-Bromo-5-Methyl-4-Pyridinecarboxylic Acid
CAS No.	1211535-59-9
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2-bromo-5-methyl-; 2-Bromo-5-methylisonicotinic acid; 5-Methyl-2-bromoisonicotinic acid; 2-Bromo-5-methyl-4-carboxypyridine; 2-Bromo-5-methylpyridine-4-carboxylic acid; 1211535-59-9; 2-Br-5-Me-4-PyCOOH
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Methyl-4-Pyridinecarboxylic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent lot-to-lot quality suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.