Description

5-Chloro-2-Fluoro-4-Pyridinecarboxylic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials where the pyridine moiety imparts specific electronic characteristics.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: Used in discovery chemistry for creating novel compound libraries and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	5-Chloro-2-Fluoro-4-Pyridinecarboxylic Acid
CAS No.	1211532-40-9
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.55 g/mol
Synonyms	5-Chloro-2-fluoropyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 5-chloro-2-fluoro-; 2-Fluoro-5-chloroisonicotinic acid; 5-Chloro-2-fluoro-4-carboxypyridine; 2-Fluoro-5-chloro-4-pyridinecarboxylic acid; 5-Chloro-2-fluoropyridine-4-carboxylic acid; 1211532-40-9 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is light-sensitive and should be handled and stored away from direct light. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.