Description

2-Cbz-2,6-Diazaspiro[3.3]Heptane Oxalate is a high-purity, advanced pharmaceutical intermediate featuring a constrained spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of complex small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of spirocyclic-based drug candidates targeting various disease pathways.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical space.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or warheads due to its rigid, three-dimensional structure.
• CNS Drug Discovery: Employed in the research of potential therapeutics for neurological disorders, leveraging the diazaspiro[3.3]heptane motif's favorable properties.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological targets and mechanisms of action.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Item	Detail
Product Name	2-Cbz-2,6-Diazaspiro[3.3]Heptane Oxalate
CAS No.	1211517-23-5
Molecular Formula	C16H20N2O6
Molecular Weight	336.34 g/mol
Synonyms	2-[(Benzyloxy)carbonyl]-2,6-diazaspiro[3.3]heptane oxalate; 2-Cbz-2,6-Diazaspiro[3.3]Heptane Oxalic Acid Salt; 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1-[(phenylmethoxy)carbonyl]-, ethanedioate (1:1); 2-(Benzyloxycarbonyl)-2,6-diazaspiro[3.3]heptane oxalate; 2-Cbz-2,6-Diaza-spiro[3.3]heptane Oxalate; 1211517-23-5; 2-Cbz-2,6-Diazaspiro[3.3]heptane hemioxalate; 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid benzyl ester oxalate
EINECS	Contact for details

Quality Control

Our 2-Cbz-2,6-Diazaspiro[3.3]Heptane Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.