Description

4-Bromo-3-Chloro-8-Methylquinoline is a halogenated quinoline derivative, a versatile and high-value organic building block. This compound is crucial for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting various disease pathways where the quinoline scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a building block for creating organic semiconductors, ligands for catalysts, and other functional organic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex quinoline motifs into larger molecular architectures.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and process chemistry optimization in both university and corporate laboratory settings.

Basic Information

Product Name	4-Bromo-3-Chloro-8-Methylquinoline
CAS No.	1211427-35-8
Molecular Formula	C10H7BrClN
Molecular Weight	256.53 g/mol
Synonyms	8-Methyl-4-bromo-3-chloroquinoline; 3-Chloro-4-bromo-8-methylquinoline; Quinoline, 4-bromo-3-chloro-8-methyl-; 4-Bromo-3-chloro-8-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-8-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.