Description

4-Amino-3-Chloro-7,8-Difluoroquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated quinoline structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the bioactivity of the difluoroquinoline scaffold.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, ligands for catalysis, and fluorescent dyes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	4-Amino-3-Chloro-7,8-Difluoroquinoline
CAS No.	1211408-87-5
Molecular Formula	C9H5ClF2N2
Molecular Weight	214.60 g/mol
Synonyms	3-Chloro-7,8-difluoro-4-quinolinamine; 4-Amino-3-chloro-7,8-difluoroquinoline; 7,8-Difluoro-4-amino-3-chloroquinoline; 3-Chloro-7,8-difluoroquinolin-4-amine; ACDL-3-Chloro-7,8-difluoro-4-quinolinamine; Building Block C9H5ClF2N2
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 4-Amino-3-Chloro-7,8-Difluoroquinoline adheres to in-house specifications developed for research and commercial scale. Every batch is analyzed using modern analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.