Description

4-Bromo-3,7,8-Trichloroquinoline is a halogenated quinoline derivative serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce specific halogenated quinoline motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer, where the quinoline scaffold is pharmacologically relevant.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated heterocycles.
• Material Science: Serves as a building block for organic semiconductors, ligands for catalysts, and photoactive compounds in electronic applications.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to create more complex, functionalized molecules.
• Dye & Pigment Industry: Intermediate for synthesizing specialized quinoline-based dyes and colorants with specific light-fastness and chromatic properties.

Basic Information

Product Name	4-Bromo-3,7,8-Trichloroquinoline
CAS No.	1211397-23-7
Molecular Formula	C9H2BrCl3N
Molecular Weight	315.38 g/mol
Synonyms	4-Bromo-3,7,8-trichloroquinoline; 3,7,8-Trichloro-4-bromoquinoline; Quinoline, 4-bromo-3,7,8-trichloro-; 4-Bromo-3,7,8-trichloro-quinoline; BTTQ (abbreviation)
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,7,8-Trichloroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.