Description

4-Amino-3-Chloro-7-Trifluoromethoxyquinoline is a high-value, multi-functional quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring amino, chloro, and trifluoromethoxy substituents, makes it an indispensable intermediate for developing novel compounds with enhanced biological activity and material properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory therapies.
• Agrochemical Research: Used in the development of next-generation pesticides, herbicides, and fungicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure.
• Chemical Synthesis: Acts as a versatile intermediate for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.
• Academic & Industrial R&D: Essential for exploratory research in medicinal chemistry and organic synthesis at universities and corporate R&D centers.

Basic Information

Product Name	4-Amino-3-Chloro-7-Trifluoromethoxyquinoline
CAS No.	1211355-50-8
Molecular Formula	C11H7ClF3N2O
Molecular Weight	275.64 g/mol
Synonyms	3-Chloro-4-amino-7-(trifluoromethoxy)quinoline; 7-(Trifluoromethoxy)-3-chloroquinolin-4-amine; 4-Amino-3-chloro-7-(trifluoromethoxy)quinoline; 4-Amino-3-chloro-7-trifluoromethoxyquinoline; 3-Chloro-7-trifluoromethoxyquinolin-4-ylamine; A-3-C-7-TFMOQ; Quinoline, 4-amino-3-chloro-7-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-7-Trifluoromethoxyquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.