Description

4-Amino-3-Chloro-6-Trifluoromethoxyquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold substituted with halogen and amino functionalities. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides and pesticides with enhanced efficacy.
• Chemical Synthesis: Used in organic synthesis to construct complex heterocyclic compounds for material science applications.
• Biochemical Research: Employed as a molecular probe or scaffold in biochemical assays and target identification studies.
• Fluorescent Dye Precursor: Potential use in the synthesis of specialized fluorophores for imaging and diagnostic applications.

Basic Information

Product Name	4-Amino-3-Chloro-6-Trifluoromethoxyquinoline
CAS No.	1211267-98-9
Molecular Formula	C₁₀H₆ClF₃N₂O
Molecular Weight	262.62 g/mol
Synonyms	3-Chloro-4-amino-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)-3-chloroquinolin-4-amine; 4-Amino-3-chloro-6-(trifluoromethoxy)quinoline; Quinoline, 4-amino-3-chloro-6-(trifluoromethoxy)-; 1211267-98-9; 4-Amino-3-chloro-6-trifluoromethoxyquinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-6-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.