Description

4-Amino-3-Bromo-5-Chloro-8-Methylquinoline is a high-purity, multi-substituted quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated and aminated structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, antimalarials, and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing new generation pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Used in the creation of organic ligands for metal-organic frameworks (MOFs) and functional dyes or pigments.
• Chemical Biology: Serves as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Organic Synthesis: Versatile intermediate for further functionalization via its reactive amino and halogen groups in cross-coupling and substitution reactions.

Basic Information

Product Name	4-Amino-3-Bromo-5-Chloro-8-Methylquinoline
CAS No.	1211156-08-9
Molecular Formula	C10H8BrClN2
Molecular Weight	271.54 g/mol
Synonyms	3-Bromo-5-chloro-8-methylquinolin-4-amine; 4-Amino-3-bromo-5-chloro-8-methylquinoline; 8-Methyl-4-amino-3-bromo-5-chloroquinoline; Quinoline, 4-amino-3-bromo-5-chloro-8-methyl-; 1211156-08-9; 4-Amino-3-bromo-5-chloro-8-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-5-Chloro-8-Methylquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.