Description

4-Bromo-3-Chloro-7-Trifluoromethoxyquinoline is a high-purity, multi-functional halogenated quinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring bromo, chloro, and trifluoromethoxy substituents, makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new-generation pesticides, herbicides, and fungicides, where the quinoline core and halogen atoms contribute to bioactivity and environmental stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, organic semiconductors, and liquid crystals due to its electron-deficient aromatic system.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create diverse chemical libraries for screening.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments, where the quinoline structure provides chromophoric properties.

Basic Information

Product Name	4-Bromo-3-Chloro-7-Trifluoromethoxyquinoline
CAS No.	1210996-42-1
Molecular Formula	C₁₁H₄BrClF₃NO
Molecular Weight	340.51 g/mol
Synonyms	4-Bromo-3-chloro-7-(trifluoromethoxy)quinoline; 7-(Trifluoromethoxy)-4-bromo-3-chloroquinoline; Quinoline, 4-bromo-3-chloro-7-(trifluoromethoxy)-; 4-Bromo-3-chloro-7-trifluoromethoxy-quinoline; 1210996-42-1
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-7-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.