Description

3,4-Dibromo-5,8-Difluoroquinoline is a high-value, multi-halogenated quinoline derivative serving as a critical synthetic intermediate. Its unique structure, featuring both bromine and fluorine substituents, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for fluorinated quinolone antibiotics and other bioactive heterocycles.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the halogen atoms contribute to binding affinity and metabolic stability.
• Material Science: Building block for creating organic electronic materials, such as charge-transport layers or fluorophores, due to its electron-deficient quinoline core.
• Chemical Synthesis: Versatile reagent for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) or nucleophilic aromatic substitution.
• Ligand & Catalyst Development: Serves as a scaffold for synthesizing novel chelating ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3,4-Dibromo-5,8-Difluoroquinoline
CAS No.	1210967-04-6
Molecular Formula	C9H3Br2F2N
Molecular Weight	322.93 g/mol
Synonyms	5,8-Difluoro-3,4-dibromoquinoline; 3,4-Dibromo-5,8-difluoroquinoline; Quinoline, 3,4-dibromo-5,8-difluoro-; 1210967-04-6
EINECS	Contact for details

Quality Control

Our 3,4-Dibromo-5,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.