Description

3,4-Dibromo-8-Trifluoromethoxyquinoline is a high-purity, multi-functional halogenated quinoline derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering unique reactivity due to its specific bromine substitution pattern and trifluoromethoxy group. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used as a versatile scaffold for developing new pesticides and herbicides, leveraging the bioactivity of the quinoline core and halogen substituents.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to introduce complex quinoline motifs.
• Ligand & Catalyst Development: Useful for constructing specialized chelating ligands in coordination chemistry and catalysis research.
• Fluorine Chemistry Studies: The trifluoromethoxy group makes it a valuable compound for investigating the effects of fluorinated alkoxy substituents on chemical properties and biological activity.

Basic Information

Product Name	3,4-Dibromo-8-Trifluoromethoxyquinoline
CAS No.	1210921-16-6
Molecular Formula	C11H4Br2F3NO
Molecular Weight	384.96 g/mol
Synonyms	8-(Trifluoromethoxy)-3,4-dibromoquinoline; 3,4-Dibromo-8-(trifluoromethoxy)quinoline; Quinoline, 3,4-dibromo-8-(trifluoromethoxy)-; 1210921-16-6; 3,4-Dibromo-8-trifluoromethoxyquinoline
EINECS	Contact for details

Quality Control

Every batch of 3,4-Dibromo-8-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.