Description

4-Bromo-3-Chloro-6-Trifluoromethylquinoline is a high-value, multi-halogenated quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture, featuring bromo, chloro, and trifluoromethyl substituents, makes it an exceptionally versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Building block for developing next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Used in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport layers.
• Ligand Synthesis: Serves as a core structure for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: An essential reagent for medicinal chemistry teams building diverse compound libraries to explore structure-activity relationships (SAR).

Basic Information

Product Name	4-Bromo-3-Chloro-6-Trifluoromethylquinoline
CAS No.	1210805-19-8
Molecular Formula	C₁₀H₄BrClF₃N
Molecular Weight	310.50 g/mol
Synonyms	6-Trifluoromethyl-4-bromo-3-chloroquinoline; 3-Chloro-4-bromo-6-(trifluoromethyl)quinoline; 4-Bromo-3-chloro-6-(trifluoromethyl)quinoline; Quinoline, 4-bromo-3-chloro-6-(trifluoromethyl)-; 1210805-19-8
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-Chloro-6-Trifluoromethylquinoline adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.