Description

4-Bromo-1,1,3,3,6-Pentamethyl-7-Nitro-2,3-Dihydro-1H-Inden-5-Ylamine is a high-purity, synthetically versatile indane derivative with a unique halogenated and nitrated structure. This compound serves as a critical advanced pharmaceutical intermediate and a valuable building block in organic synthesis, enabling the development of novel chemical entities. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogen and nitro functional groups for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations due to its reactive bromine and amine sites.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers and advanced organic materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	4-Bromo-1,1,3,3,6-Pentamethyl-7-Nitro-2,3-Dihydro-1H-Inden-5-Ylamine
CAS No.	1210378-97-4
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	5-Amino-4-bromo-1,1,3,3,6-pentamethyl-7-nitro-2,3-dihydro-1H-indene; 4-Bromo-1,1,3,3,6-pentamethyl-7-nitroindan-5-amine; 1H-Inden-5-amine, 4-bromo-2,3-dihydro-1,1,3,3,6-pentamethyl-7-nitro-; 1210378-97-4; Bromo-pentamethyl-nitro-dihydroindenamine; Advanced Indane Derivative Intermediate
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1,1,3,3,6-Pentamethyl-7-Nitro-2,3-Dihydro-1H-Inden-5-Ylamine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.