Description

4-Amino-3-Chloro-8-Fluoroquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring strategically positioned amino, chloro, and fluoro substituents on the quinoline core, makes it a critical intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom enhances bioavailability and stability.
• Material Science: Acts as a building block for creating specialized organic ligands, dyes, and functional polymers with specific electronic properties.
• Chemical Synthesis: Utilized in cross-coupling reactions and other advanced transformations to introduce the quinoline scaffold into more complex molecular structures.
• Biochemical Research: Employed as a standard or probe in biochemical assays and pharmacological studies due to its distinct fluorinated quinoline structure.

Basic Information

Product Name	4-Amino-3-Chloro-8-Fluoroquinoline
CAS No.	1210324-93-8
Molecular Formula	C9H6ClFN2
Molecular Weight	196.61 g/mol
Synonyms	8-Fluoro-4-amino-3-chloroquinoline; 3-Chloro-8-fluoroquinolin-4-amine; 4-Amino-3-chloro-8-fluoro-quinoline; 1210324-93-8; 4-Quinolinamine, 3-chloro-8-fluoro-; 3-Chloro-8-fluoro-4-quinolinamine
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-8-Fluoroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.