Description

4-Bromo-3-Chloro-5,8-Difluoroquinoline is a high-value, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research institutions and industrial R&D teams focused on creating novel active ingredients, such as pharmaceuticals, crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting infectious diseases or cancer.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for creating functionalized organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Synthesis: A versatile reagent for introducing halogenated quinoline motifs into more complex molecular architectures via cross-coupling reactions.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and process development in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	4-Bromo-3-Chloro-5,8-Difluoroquinoline
CAS No.	1210275-42-5
Molecular Formula	C9H3BrClF2N
Molecular Weight	278.48 g/mol
Synonyms	4-Bromo-3-chloro-5,8-difluoroquinoline; 5,8-Difluoro-4-bromo-3-chloroquinoline; Quinoline, 4-bromo-3-chloro-5,8-difluoro-; 1210275-42-5; 4-Br-3-Cl-5,8-F2-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-5,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.