Description

4-Amino-7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block characterized by its quinoline core, amino group, and trifluoromethyl substituent. This compound matters for its critical role in medicinal chemistry and advanced material science, where it serves as a versatile precursor for synthesizing complex molecules with tailored properties. Pharmaceutical researchers and fine chemical manufacturers need this intermediate for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials, leveraging its unique chemical reactivity and the desirable characteristics imparted by the fluorine atoms.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for anticancer, antiviral, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags and molecular probes for diagnostic and research applications.
• Academic & Industrial R&D: Essential for synthetic chemistry research in universities and corporate laboratories exploring new heterocyclic compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	4-Amino-7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1210221-54-7
Molecular Formula	C₁₃H₁₁F₃N₂O₂
Molecular Weight	284.24 g/mol
Synonyms	Ethyl 4-Amino-7-(trifluoromethyl)quinoline-3-carboxylate; 4-Amino-7-trifluoromethylquinoline-3-carboxylic acid ethyl ester; 7-(Trifluoromethyl)-4-aminoquinoline-3-carboxylic acid ethyl ester; 4-Amino-7-trifluoromethyl-3-quinolinecarboxylic acid ethyl ester; AATQCE; 1210221-54-7; Ethyl 4-amino-7-(trifluoromethyl)-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.