Description

4-Amino-3-Chloro-5,8-Difluoroquinoline is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and aminated structure makes it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Synthesis: Used to develop advanced fungicides and herbicides, leveraging the difluoroquinoline scaffold for enhanced efficacy and environmental profile.
• Organic Light-Emitting Diodes (OLEDs): Serves as a core structure or dopant material in the development of electron-transport or emissive layers for display and lighting technologies.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Coordination Chemistry & Catalysis: Potential ligand for metal complexes used in catalytic processes or as functional materials.

Basic Information

Product Name	4-Amino-3-Chloro-5,8-Difluoroquinoline
CAS No.	1209923-65-8
Molecular Formula	C9H5ClF2N2
Molecular Weight	214.60 g/mol
Synonyms	3-Chloro-5,8-difluoroquinolin-4-amine; 4-Amino-3-chloro-5,8-difluoroquinoline; 5,8-Difluoro-3-chloroquinolin-4-amine; Quinoline, 4-amino-3-chloro-5,8-difluoro-; 1209923-65-8; 4-Amino-3-chloro-5,8-difluorquinolin; 3-Chloro-5,8-difluoro-4-quinolinamine
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-5,8-Difluoroquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.