Description

4-Amino-3-Chloro-6,8-Difluoroquinoline is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern chemical synthesis. Its unique halogenated and aminated structure makes it an essential building block for creating complex molecules with targeted biological and material properties. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs) targeting bacterial infections.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging its difluoroquinoline core for enhanced bioactivity.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and creating specialized chemical libraries.
• Dye and Pigment Intermediate: Acts as a precursor for synthesizing specialized heterocyclic dyes and functional colorants.

Basic Information

Product Name	4-Amino-3-Chloro-6,8-Difluoroquinoline
CAS No.	1209810-36-5
Molecular Formula	C9H5ClF2N2
Molecular Weight	214.60 g/mol
Synonyms	3-Chloro-6,8-difluoro-4-quinolinamine; 4-Quinolinamine, 3-chloro-6,8-difluoro-; 6,8-Difluoro-3-chloro-4-aminoquinoline; 4-Amino-3-chloro-6,8-difluoro-quinoline; ACD-3-Chloro-6,8-difluoro-4-quinolinamine; 1209810-36-5; 3-Chloro-6,8-difluoroquinolin-4-amine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Chloro-6,8-Difluoroquinoline is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.