Description

4-Amino-6-Bromo-3-Chloroquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated quinoline structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for anticancer, antiviral, and antimicrobial applications.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core.
• Material Science: Serves as a building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other functional electronic materials.
• Dye & Pigment Synthesis: Employed in the production of advanced, light-fast dyes and pigments due to the stable quinoline chromophore.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for biological imaging and diagnostic assays.
• Catalyst Ligand Precursor: The amino and halogen groups allow for functionalization into complex ligands for transition metal catalysis.

Basic Information

Product Name	4-Amino-6-Bromo-3-Chloroquinoline
CAS No.	1209752-90-8
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	6-Bromo-3-chloro-4-aminoquinoline; 3-Chloro-6-bromo-4-quinolinamine; 4-Quinolinamine, 6-bromo-3-chloro-; 4-Amino-6-bromo-3-chloroquinoline; 6-Bromo-3-chloro-quinolin-4-ylamine; 4-Amino-3-chloro-6-bromoquinoline; 1209752-90-8
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-6-Bromo-3-Chloroquinoline is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our products are suitable for research and scale-up applications, with comprehensive specifications covering identity, purity, and impurity profiles. A Certificate of Analysis (COA) is provided with each shipment, detailing the results from advanced techniques such as HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.