Description

4-Bromo-3-Chloro-7,8-Difluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique halogen substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of antibacterial and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.
• Catalyst Ligand Development: Acts as a scaffold for creating novel ligands used in transition metal catalysis for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	4-Bromo-3-Chloro-7,8-Difluoroquinoline
CAS No.	1209680-95-4
Molecular Formula	C9H3BrClF2N
Molecular Weight	278.48 g/mol
Synonyms	4-Bromo-3-chloro-7,8-difluoroquinoline; 7,8-Difluoro-4-bromo-3-chloroquinoline; Quinoline, 4-bromo-3-chloro-7,8-difluoro-; 1209680-95-4; 4-Br-3-Cl-7,8-F2-quinoline
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Chloro-7,8-Difluoroquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles by HPLC, NMR, and LC-MS is supplied with each shipment. Our quality commitment supports applications from early-stage R&D to cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.