Description

4-Amino-3-Chloro-8-Trifluoromethylquinoline is a high-purity, multi-functional quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active compounds. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Research: Used as a building block for developing new pesticides, herbicides, and fungicides with enhanced efficacy.
• Organic Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Material Science: Investigated for the development of advanced organic electronic materials and specialty dyes.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and reaction mechanisms.
• Fluorinated Compound Synthesis: The trifluoromethyl group makes it a valuable synthon for introducing fluorine into target molecules to modulate their properties.

Basic Information

Product Name	4-Amino-3-Chloro-8-Trifluoromethylquinoline
CAS No.	1209602-62-9
Molecular Formula	C10H6ClF3N2
Molecular Weight	246.62 g/mol
Synonyms	3-Chloro-4-amino-8-(trifluoromethyl)quinoline; 8-Trifluoromethyl-4-amino-3-chloroquinoline; 4-Amino-3-chloro-8-(trifluoromethyl)quinoline; Quinoline, 4-amino-3-chloro-8-(trifluoromethyl)-; 1209602-62-9; 4-Amino-3-chloro-8-trifluoromethyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-8-Trifluoromethylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent quality. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports your R&D and production needs with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.