Description

(1-(3-Chlorophenyl)Cyclopropyl)Methanamine Hydrochloride is a high-purity, synthetically valuable organic building block and pharmaceutical intermediate. Its core value proposition lies in its unique cyclopropylamine structure, which is crucial for imparting specific biological activity and metabolic stability in advanced drug discovery programs. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, cardiovascular diseases, or anti-infective agents.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Process Chemistry Development: Used in route scouting, scale-up studies, and the development of robust, GMP-compliant synthetic pathways for clinical and commercial API manufacturing.
• Biochemical Tool Compound: Potential use in pharmacological assays and as a reference standard for analytical method development and validation.
• Custom Synthesis Building Block: Employed in the contract research and manufacturing (CRAM) sector for the bespoke synthesis of complex molecules.

Basic Information

Product Name	(1-(3-Chlorophenyl)Cyclopropyl)Methanamine Hydrochloride
CAS No.	1209173-54-5
Molecular Formula	C10H13Cl2N
Molecular Weight	218.12 g/mol
Synonyms	1-[(3-Chlorophenyl)cyclopropyl]methanamine hydrochloride; (1-(3-Chlorophenyl)cyclopropyl)methanamine HCl; 3-Chloro-α-(cyclopropylmethyl)benzylamine hydrochloride; 1-(3-Chlorophenyl)cyclopropanemethylamine hydrochloride; (3-Chlorophenyl)cyclopropylmethylamine hydrochloride; 1-(3-Chloro-phenyl)-cyclopropylmethylamine hydrochloride; α-(Cyclopropylmethyl)-3-chlorobenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1-(3-Chlorophenyl)Cyclopropyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.