Description

4-Amino-3-Bromo-6-Ethylquinoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both amino and bromo substituents on the quinoline core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates, particularly for antimalarial, anticancer, and antimicrobial applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinoline scaffold can impart specific biological activity.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Synthesis: The reactive bromo and amino groups allow for sequential functionalization via cross-coupling (e.g., Suzuki, Buchwald-Hartwig) and other reactions, enabling library synthesis for high-throughput screening.
• Dye and Pigment Industry: Acts as an intermediate for the production of specialized quinoline dyes and fluorescent markers.

Basic Information

Item	Details
Product Name	4-Amino-3-Bromo-6-Ethylquinoline
CAS No.	1209062-73-6
Molecular Formula	C11H11BrN2
Molecular Weight	251.12 g/mol
Synonyms	3-Bromo-4-amino-6-ethylquinoline; 6-Ethyl-3-bromo-4-quinolinamine; 4-Quinolinamine, 3-bromo-6-ethyl-; 4-Amino-6-ethyl-3-bromoquinoline; 3-Bromo-6-ethylquinolin-4-amine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Bromo-6-Ethylquinoline is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.