Description

4-Amino-3-Bromo-5-Chloro-8-Methoxyquinoline is a high-purity, multi-substituted quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chemical building block for the development of novel active molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting infectious diseases or cancer.
• Agrochemical Research: Building block for developing new fungicides, herbicides, or insecticides with novel modes of action.
• Material Science: Used in the synthesis of functional organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology: Serves as a probe or scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Academic & Contract Research: Essential reagent for synthetic organic chemistry research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	4-Amino-3-Bromo-5-Chloro-8-Methoxyquinoline
CAS No.	1209057-14-6
Molecular Formula	C10H8BrClN2O
Molecular Weight	287.54 g/mol
Synonyms	8-Methoxy-3-bromo-5-chloroquinolin-4-amine; 3-Bromo-5-chloro-8-methoxy-4-quinolinamine; 4-Quinolinamine, 3-bromo-5-chloro-8-methoxy-; 4-Amino-3-bromo-5-chloro-8-methoxyquinoline; 3-Bromo-5-chloro-8-methoxyquinolin-4-amine
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-5-Chloro-8-Methoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, from research to GMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.