Description

4-Bromo-3,8-dichloro-5-methoxyquinoline is a halogenated quinoline derivative, a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of antimalarial, antibacterial, and anticancer agents based on the quinoline scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and pesticides, where the quinoline core provides potent biological activity.
• Material Science Research: Serves as a building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its electron-deficient aromatic system.
• Chemical Biology & Proteomics: Employed as a reactive handle or a core structure in the design of chemical probes, enzyme inhibitors, and molecular tags for biological studies.
• Dye & Pigment Intermediate: Acts as a precursor for the synthesis of specialized quinoline-based dyes and pigments with specific light-absorption or emission properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in methodological development and discovery chemistry.

Basic Information

Product Name	4-Bromo-3,8-dichloro-5-methoxyquinoline
CAS No.	1208900-36-0
Molecular Formula	C₁₀H₆BrCl₂NO
Molecular Weight	307.97 g/mol
Synonyms	4-Bromo-3,8-dichloro-5-methoxyquinoline; 5-Methoxy-4-bromo-3,8-dichloroquinoline; Quinoline, 4-bromo-3,8-dichloro-5-methoxy-; 3,8-Dichloro-4-bromo-5-methoxyquinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,8-dichloro-5-methoxyquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.