Description

4-Bromo-3,8-Dichloroquinoline is a halogenated quinoline derivative, a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise molecular architecture makes it a critical building block for constructing complex heterocyclic frameworks, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals developing novel active ingredients, where its unique substitution pattern enables targeted molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with specific modes of action.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline core into more complex molecules.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Academic & Contract Research: A valuable reagent for methodological studies and library synthesis in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	4-Bromo-3,8-Dichloroquinoline
CAS No.	1208839-64-8
Molecular Formula	C9H4BrCl2N
Molecular Weight	277.95 g/mol
Synonyms	4-Bromo-3,8-dichloroquinoline; 3,8-Dichloro-4-bromoquinoline; Quinoline, 4-bromo-3,8-dichloro-; 1208839-64-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,8-Dichloroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.