Description

4-Bromo-3-Chloro-7-Fluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogen substitution pattern enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for enhanced bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex quinoline scaffolds into larger molecular architectures.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	4-Bromo-3-Chloro-7-Fluoroquinoline
CAS No.	1208814-10-1
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	4-Bromo-3-chloro-7-fluoroquinoline; 7-Fluoro-4-bromo-3-chloroquinoline; Quinoline, 4-bromo-3-chloro-7-fluoro-; 1208814-10-1; 4-Br-3-Cl-7-F-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-7-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.