Description

3,4-Dibromo-6-Trifluoromethylquinoline is a high-value, multi-functional halogenated quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the development of novel active compounds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers.
• Ligand and Catalyst Development: The quinoline core and halogen substituents make it a valuable scaffold for designing novel ligands in transition metal catalysis.
• Fluorescent Probe Synthesis: Utilized in creating specialized fluorophores for bio-imaging and diagnostic applications due to its derivatizable structure.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, including cross-coupling and halogen-metal exchange reactions.

Basic Information

Product Name	3,4-Dibromo-6-Trifluoromethylquinoline
CAS No.	1208619-25-3
Molecular Formula	C10H4Br2F3N
Molecular Weight	354.95 g/mol
Synonyms	6-(Trifluoromethyl)-3,4-dibromoquinoline; 3,4-Dibromo-6-(trifluoromethyl)quinoline; Quinoline, 3,4-dibromo-6-(trifluoromethyl)-; DBTFQ
EINECS	Contact for details

Quality Control

Our 3,4-Dibromo-6-Trifluoromethylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring suitability for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.