Description

4-Bromo-3-Chloro-8-Ethylquinoline is a high-purity, multi-substituted quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its unique halogenated and alkylated structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Synthesis: An essential reagent for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex quinoline motifs.
• Ligand & Catalyst Development: Employed in the design of novel chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and fluorescent markers.

Basic Information

Product Name	4-Bromo-3-Chloro-8-Ethylquinoline
CAS No.	1208613-93-7
Molecular Formula	C₁₁H₉BrClN
Molecular Weight	270.55 g/mol
Synonyms	8-Ethyl-4-bromo-3-chloroquinoline; 3-Chloro-4-bromo-8-ethylquinoline; 4-Bromo-3-chloro-8-ethyl-quinoline; Quinoline, 4-bromo-3-chloro-8-ethyl-; 1208613-93-7; 8-Ethyl-3-chloro-4-bromoquinoline
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-Chloro-8-Ethylquinoline adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.