Description

4-Bromo-3,5-dichloro-8-methoxyquinoline is a high-purity, multi-halogenated quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or acting as kinase inhibitors.
• Agrochemical Research: Used in the development of new-generation fungicides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline moiety into more complex molecules.
• Ligand Synthesis: Useful for creating novel chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Bromo-3,5-Dichloro-8-Methoxyquinoline
CAS No.	1208457-43-5
Molecular Formula	C₁₀H₆BrCl₂NO
Molecular Weight	307.97 g/mol
Synonyms	8-Methoxy-4-bromo-3,5-dichloroquinoline; 3,5-Dichloro-4-bromo-8-methoxyquinoline; 4-Bromo-3,5-dichloro-8-methoxy-quinoline; Quinoline, 4-bromo-3,5-dichloro-8-methoxy-; 1208457-43-5; 4-Br-3,5-Cl₂-8-MeO-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,5-dichloro-8-methoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.