Description

4-Bromo-3-Chloro-7-Methoxyquinoline is a high-purity, multi-functional halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides distinct reactivity for constructing complex heterocyclic systems. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or possessing antimicrobial properties.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and plant growth regulators due to the bioactive quinoline core.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create diverse chemical libraries.
• Academic & Contract Research: Essential for fundamental research in medicinal chemistry and organic methodology development within universities and CROs.

Basic Information

Product Name	4-Bromo-3-Chloro-7-Methoxyquinoline
CAS No.	1208452-88-3
Molecular Formula	C₁₀H₇BrClNO
Molecular Weight	272.53 g/mol
Synonyms	4-Bromo-3-chloro-7-methoxyquinoline; 7-Methoxy-4-bromo-3-chloroquinoline; 3-Chloro-4-bromo-7-methoxyquinoline; Quinoline, 4-bromo-3-chloro-7-methoxy-; 1208452-88-3; 4-Br-3-Cl-7-OMe-quinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-7-Methoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades, from research (≥95%) to advanced pharmaceutical intermediate (≥98%) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.