Description

2-Bromo-3,6-Difluorophenol is a halogenated and fluorinated phenolic compound that serves as a versatile and high-value synthetic intermediate. Its unique structure, featuring bromine and fluorine substituents on the aromatic ring, makes it a critical building block for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluorophenol unit can enhance compound efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Polymer Modification: Employed to introduce halogenated phenolic groups into polymer chains, altering properties like flame retardancy, thermal stability, or solubility.
• Organic Synthesis & Catalysis: Acts as a specialized reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalyst design.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and material science research, enabling the exploration of new chemical spaces and structure-activity relationships.

Basic Information

Product Name	2-Bromo-3,6-Difluorophenol
CAS No.	1208077-18-2
Molecular Formula	C6H3BrF2O
Molecular Weight	208.99 g/mol
Synonyms	3,6-Difluoro-2-bromophenol; 2-Bromo-3,6-difluorophenol; Phenol, 2-bromo-3,6-difluoro-; 2-Bromo-3,6-difluoro-1-hydroxybenzene; 1-Bromo-2,5-difluoro-6-hydroxybenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,6-Difluorophenol is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical applications, ensuring traceability and reliability for critical R&D and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.