Description

2-Cyclopropylmethyl-2,5-Diaza-Bicyclo[2.2.1]Heptane Di-Trifluoroacetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique, constrained bicyclic diaza structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking to develop new drug candidates with enhanced selectivity and potency.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its rigid, three-dimensional scaffold.
• Ligand Synthesis: Serves as a precursor for complex ligands in catalysis and receptor-binding studies.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological pathways and target validation.
• Process Chemistry Development: Scaled for use in route scouting and optimization for potential Good Manufacturing Practice (GMP) production.
• Academic Research: Utilized in universities and research institutes for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	2-Cyclopropylmethyl-2,5-Diaza-Bicyclo[2.2.1]Heptane Di-Trifluoroacetic Acid
CAS No.	1208075-35-7
Molecular Formula	C13H18F6N2O4
Molecular Weight	380.29 g/mol
Synonyms	2-(Cyclopropylmethyl)-2,5-diazabicyclo[2.2.1]heptane ditrifluoroacetate; 2,5-Diaza-bicyclo[2.2.1]heptane, 2-(cyclopropylmethyl)-, bis(trifluoroacetate); 2-Cyclopropylmethyl-2,5-diazabicyclo[2.2.1]heptane bis(trifluoroacetic acid) salt; 2-CPM-2,5-DABCO TFA Salt; 2-Cyclopropylmethyl-2,5-diazabicyclo[2.2.1]heptane di-TFA; 1208075-35-7; Bicyclo[2.2.1]heptane-2,5-diamine, N2-(cyclopropylmethyl)-, bis(2,2,2-trifluoroacetate)
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylmethyl-2,5-Diaza-Bicyclo[2.2.1]Heptane Di-Trifluoroacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with the standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.