Description

6-Fluoro-4-Nitro-3H-Isobenzofuran-1-One is a high-purity fluorinated and nitrated isobenzofuranone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring both electron-withdrawing substituents, makes it a valuable building block for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of fluorinated bioactive molecules.
• Agrochemical Research: Used in creating advanced intermediates for new-generation herbicides, fungicides, and insecticides that leverage fluorine chemistry for enhanced efficacy and stability.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex fused-ring systems and heterocycles due to its reactive carbonyl and nitro groups.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	6-Fluoro-4-Nitro-3H-Isobenzofuran-1-One
CAS No.	1207453-90-4
Molecular Formula	C8H4FNO4
Molecular Weight	197.12 g/mol
Synonyms	6-Fluoro-4-nitro-1(3H)-isobenzofuranone; 4-Nitro-6-fluoroisobenzofuran-1(3H)-one; 6-Fluoro-4-nitroisobenzofuran-1(3H)-one; 3H-Isobenzofuran-1-one, 6-fluoro-4-nitro-; 1207453-90-4; 6-Fluoro-4-nitro-phthalide
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Nitro-3H-Isobenzofuran-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and industrial applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.