Description

1-Bromo-5-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which provides distinct reactive sites for selective cross-coupling and functionalization reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used to construct novel heterocyclic compounds for the development of new pesticides and herbicides.
• Material Science: Building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Chemical Library Synthesis: Employed in combinatorial and parallel synthesis for generating diverse compound libraries for high-throughput screening.
• Academic & R&D: Fundamental research reagent for studying reaction mechanisms and developing new synthetic methodologies in organic chemistry.

Basic Information

Product Name	1-Bromo-5-Chloroisoquinoline
CAS No.	1207448-41-6
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	5-Chloro-1-bromoisoquinoline; Isoquinoline, 1-bromo-5-chloro-; 1-Bromo-5-chloro-isoquinoline; 1207448-41-6
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Chloroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.