Description

5-Fluoro-1,2,3,4-Tetrahydroquinoline Hydrochloride is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science: Acts as a precursor for specialty chemicals, dyes, and advanced polymers requiring fluorinated quinoline structures.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and exploring new chemical spaces in heterocyclic chemistry.
• Custom Synthesis: A starting point for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	5-Fluoro-1,2,3,4-Tetrahydroquinoline Hydrochloride
CAS No.	1207176-29-1
Molecular Formula	C9H11ClFN
Molecular Weight	187.64 g/mol
Synonyms	5-Fluoro-1,2,3,4-tetrahydroquinoline HCl; 5-Fluoro-1,2,3,4-tetrahydroquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-fluoroquinoline hydrochloride; 5-Fluoro-3,4-dihydro-2H-quinoline hydrochloride; 5-Fluoro-THQ HCl; 5-F-THQ·HCl
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1,2,3,4-Tetrahydroquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all specifications are available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.