Description

3-(2-Dimethylamino-Ethyl)-1,3,8-Triaza-Spiro[4.5]Decane-2,4-Dione is a sophisticated spirocyclic organic compound featuring a unique triaza-spirodecane core structure, which is of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate or building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Integral to the development pathway of new Active Pharmaceutical Ingredients (APIs) requiring complex heterocyclic architectures.
• Neurological & Psychiatric Drug Synthesis: Building block for potential therapeutics aimed at conditions such as depression, anxiety, or cognitive disorders.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	3-(2-Dimethylamino-Ethyl)-1,3,8-Triaza-Spiro[4.5]Decane-2,4-Dione
CAS No.	1206970-51-5
Molecular Formula	C13H22N4O2
Molecular Weight	266.34 g/mol
Synonyms	1,3,8-Triazaspiro[4.5]decane-2,4-dione, 3-[2-(dimethylamino)ethyl]-; 3-(2-Dimethylaminoethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione; Spiro[4.5]decane-2,4-dione, 3-[2-(dimethylamino)ethyl]-1,3,8-triaza-; UNII-9J8F6F8Q0F; 9J8F6F8Q0F; 3-(2-(Dimethylamino)ethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
EINECS	Contact for details

Quality Control

Our production of 3-(2-Dimethylamino-Ethyl)-1,3,8-Triaza-Spiro[4.5]Decane-2,4-Dione adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development under various quality frameworks, including research grade and cGMP standards for advanced clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.