Description

4-[6-[4-(1-Methylethoxy)Phenyl]Pyrazolo[1,5-A]Pyrimidin-3-Yl]-Quinoline is a high-purity, advanced pharmaceutical intermediate and research chemical with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted kinase inhibitors and other biologically active molecules.
• Oncology Research: Serves as a core scaffold for developing potential anti-cancer compounds due to its pyrazolopyrimidine-quinoline hybrid structure.
• Chemical Biology: Used in probe and tool compound development for studying specific enzyme pathways and protein interactions.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Custom Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	4-[6-[4-(1-Methylethoxy)Phenyl]Pyrazolo[1,5-A]Pyrimidin-3-Yl]-Quinoline
CAS No.	1206711-16-1
Molecular Formula	C24H20N4O
Molecular Weight	380.45 g/mol
Synonyms	4-[6-[4-(Isopropoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline; 4-(6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline; Quinoline, 4-[6-[4-(1-methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-; CAS 1206711-16-1; 4-(6-(4-Isopropoxyphenyl)-1H-pyrazolo[1,5-a]pyrimidin-3-yl)quinoline (tautomeric form)
EINECS	Contact for details

Quality Control

Our 4-[6-[4-(1-Methylethoxy)Phenyl]Pyrazolo[1,5-A]Pyrimidin-3-Yl]-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.